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The BioJeL laboratory: A decisive tool for research

Published on 06/01/2010 in Scientific research

Storabiologiste

On the 21st of June 2010, the Jérôme Lejeune Institute launched the new website www.crb-instituelejeune.com. It enables researchers from all over the world to have an access to the genetic tissue material catalogue taken from samples which have been treated and cryopreserved by the Biojel laboratory. Story of how a unique centre came into existence.

During the summer of 2006, the Jérôme Lejeune Foundation launched a call for donations in view of the construction and installation of a laboratory conceived to become a reference centre in biological resources (CBR) for genetic intellectual disabilities.

The objective was to create a collection of genetic material (DNA, RNA, lymphocytes, etc.) coming from patients with genetic intellectual diseases so that they could be treated, cryopreserved and made available for researchers. Thus, this biological resource centre aims at stimulating and facilitating researchers work on genetic intellectual disorders by giving scientists the means to better understand these diseases. Starting this long-awaited centre therefore fully responds to the mission of the Jérôme Lejeune Foundation and the Jérôme Lejeune Institute.

Of course, the installation of this laboratory on the very site of the Jérôme Lejeune Institute is a marvellous asset: requesting consent for samples, doing the blood samples and, finally, ultra rapid transport and treatment of these biological resources are made considerably easier.

Concretely, this project involves the construction of a laboratory dedicated to cellular and tissue culture, a versatile platform for biology and genetics which has the means to insure the conservation of the samples.
It was therefore necessary to insure specific premises, scientific material and personnel. This laboratory’s construction and equipment-called Biojel- were entirely financed by the generosity of the Foundation’s donators.

Launched in October 2006, the work was achieved at the beginning of the term of 2007. In the months that followed, the necessary material was bought and installed, starting with the largest appliances: freezers (with conservation temperatures from -80° to -150°), centrifuges, fume hoods, microscopes, etc. At the beginning of the term of 2008, after having hired an engineer in biology, the laboratory’s activity was launched with the arrival of the first samples. As expected, it took the CBR just over 18 months to gather 500 samples, to which will soon be added the various collections from the Jérôme Lejeune Institute from 2008 which were being preserved outside the centre.

Very strict norms were observed during the conception of the laboratory and not-less strict specifications were observed which allows Biojel to be officially recognized as a biology resource centre.

This referencing is important not only for the patients who are called upon for samples but also for the international community of researchers. This collections of samples, currently enables the Jerome Lejeune Institute to lead the Transcriptome project (see box alongside)

This collection being designed for all researchers, a website (www.crb-institutlejeune.com) was launched last 21st of June. Researchers will be able to access the CBR’s online catalogue and order the samples they need for their work. Other services are offered online, and in particular, the treatment and cryopreservation of genetic material issued from samples taken elsewhere.


centrifugeurBioJeLThis double context -specialized consultation and research objectives- which prevailed in the launching of Biojel makes the CBR a unique centre. Enabling researcher from all over the world to be provided with the genetic material needed in their work should help them to move through decisive stages towards finding a treatment for genetic intellectual disabilities.


As this Biojel collection is being put at the disposition of researchers, the Foundation and the Institute would, once again, like to thank their numerous and generous donators who financed this project.

 

Awel donates a centrifuge to the Biojel laboratory

Specialized in laboratory centrifuges that it conceives and builds in France, the Awel society donated one of its latest, high technology devices to the Institute in 2010. This particularly efficient Awel centrifuge enables one to divide the various tasks (cellular biology and molecular biology) between the two centrifuges which are now available in in the laboratory.


Thus, temperature and congestion issues during the various stages of centrifugation are avoided!

The Transciptome Project: :

It consists in a comparative genotype-phenotype study: it aims at comparing the symptoms presented by each patient with its genome. In time, it will enable researchers to identify the genes which are more significant in intellectual deficiency

 If you want to help the programme you can make a donation!

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