Jérôme Lejeune Institute Medical Office

Petite fille trisomique 21



Jean-Marie Schmitz

President of the Jérôme Lejeune Institute





Professor Marie-Odile Réthoré: “Always tell the truth.”

Medical Director of the Jérôme Lejeune Institute




  • The Jérôme Lejeune Institute: a structure dedicated to care

    Created in 1998, the Jérôme Lejeune Institute welcomes more than 4,000 patients each year to its specialised medical office which has become the referral centre for the French Social Security and follows 6,500 cases!

  • The medical office: expertise combined with humanity

    Bringing together expertise Within the Jérôme Lejeune Institute Medical Office, healthcare professionals contribute their knowledge on the illnesses themselves and all aspects of the patients’ lives. The Institute welcomes families of patients suffering from various genetic defects (trisomy 21, fragile X syndrome, cri du chat, chromosomal defects, Rett syndrome, Williams-Beuren syndrome, Prader-Willi syndrome, Angelman syndrome, etc.) or suffering from an intellectual disability whose origins are not yet explained.

  • Personalised accompaniment.

    Communicating with the medical world Sensitising healthcare professionals to the problems of persons suffering from genetic illnesses with intellectual disabilities is at the heart of the activity of the Institute and its staff through the intermediary of networks such Intelli’Cure or Oncodefi. In order that knowledge be harmonised, it is important to create links between the different health stakeholders which deal with patients and their families and to generate resources that are useful for all researchers.


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